• Research
  • Structural research on pathogens of emerging and re-emerging infectious diseases


    Emerging and re-emerging infectious diseases are one of the major threats to human health and economic loss. This project focuses on the molecular mechanism of the complete biology of emerging and re-emerging pathogens, including EV71/CAV, tubercolosis, heptatitis A virus, coronavirus, influenza virus and bunyavirus. We will dissect the molecular mechanisms underlying pathogens infection/entry, replication and transcription, as well as maturation/releasing, and provide new strategies for anti-infection drug discovery based on the structural information acquired.