On June 3^rd, Academician Shao Feng, senior researcher and deputy director of the Beijing Institute of Life Sciences, spoke at Hundred Years Pharmacy Lecture at the School of Pharmacy, and discussed  Pyroptosis, Inflammation and Tumor Immunity for teachers and students of Nankai University.

In the report, Shao introduced the study of the mechanism of the process of cell pyrolysis, redefined it by identifying the Gasdermin family membrane perforating protein, and gave a detailed explanation of the new direction of cell death and immune research. He further expounded upon the relationship between cell pyrolysis and the toxicological side effects of chemotherapy drugs, and the key mechanism of the pyrolysis-induced anti-tumor immune response.

Academician Shao is now the deputy director of scientific research at the Beijing Institute of Biological Sciences. He is a world leader in the field of innate immune receptor research. He was elected as an academician of the Chinese Academy of Sciences in 2015, a foreign member of the European Molecular Biology Organization (EMBO) in the same year, a fellow of the American Academy of Microbiology in 2016, and a fellow of the German National Academy of Sciences in 2019. He has made important contributions in the field of innate immunity and pyroptosis, and identified multiple intracellular immune receptors against bacteria, providing new targets for drug development in sepsis and inflammatory diseases. He has published more than 100 academic papers and has published 17 research papers in Nature, Science, and Cell journals as the corresponding author, with a total of nearly 20,000 citations. Additionally, he has won the Future Science Award, Qiushi Outstanding Scientist Award, HHMI International Young Scientist Award, Ewensige Young Scientist of the International Protein Society Awards and many other important awards.

(Reported and photographed by Nan Zhao, translated by Wenhan Lin, edited by Daniel Stefan and JianjingYun)