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08.17 2022NKU Research Team Uses CLL-1 CAR-T Cell Therapy for Adult Acute Myeloid Leukemia for the First Time and Makes Breakthroughs
Recently, the team headed by Prof. Zhao Mingfeng of the First Central Hospital Affiliated to Nankai University and the team headed by Prof. Zhang Hongkai of the School of Life Sciences of Nankai University cracked the problem of R/R AML CAR-T treatment through cooperation. The relevant findings were published online in the international prestigious Journal of Hematology Oncology (IF:23.168) on July 7.In this clinical study, the teams applied CAR-T cell therapy for the new target CLL-1 to adult
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08.11 2022Latest Findings of NKU's Research Team in the Field of Autophagy Published in Leading Journal The Plant Cell
Prof. Li Lei from the College of Life Sciences, Nankai University formed an international joint research team with Prof. Harvey Millar of the University of Western Australia and Prof. Marisa Otegui of the University of Wisconsin. Using stable isotope metabolic labeling and a protein turnover analysis platform created by mass spectrometry technology, in conjunction with cell biology, metabolomics analysis and biochemical experimental evidence, the team systematically compared the differences in t
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07.28 2022NKU Team Makes Key Progress in the Field of Nitric Oxide-regulated Regeneration of Artificial Vascular Tissues
Recently, the research group headed by Prof. Zhao Qiang from the State Key Laboratory of Medicinal Chemical Biology of Nankai University made new progress in the preparation of new bio-hybrid artificial blood vessels and regulation of their tissue regeneration. The team put forward a new strategy for artificial blood vessels to improve tissue regeneration and restructuring through local release of nitric oxide (NO), and designed and prepared bio-hybrid artificial blood vessels with NO slow-relea
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07.27 2022NKU Research Team Spearheaded the Completion of First Animal Experiment on Interventional Brain-Computer Interface (BCI) in China
Interventional brain-computer interface was realized on the sheep brain for the first time in ChinaProf. Duan Feng of Nankai University at the experiment siteOn June 25, an animal experiment on Chinas first independently developed interventional Brain-Computer Interface (BCI) was completed in Beijing. The interventional BCI for this experiment was developed by the research team led by Prof. Duan Feng of the College of Artificial Intelligence, Nankai University, in partnership with Shanghai Heart
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07.07 2022Nankai Team Made a New Progress in the Research of Evasion from the Host Immune System by Neonatal Meningitis-causing Pathogens
Bacterial meningitis is one of the top ten causes of infection-related deaths worldwide which has high rates of morbidity and mortality in newborns and the elderly. Neonatal meningitis-causing Escherichia coli(NMEC) is the leading cause of meningitis in newborns worldwide. The brain was long regarded as a highly immuneprivileged site which would benefits for bacterial survival once they invade in the brain. However, recent studies showed that some cells in brain, including microglia and astrocy
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06.29 2022Nonlinear Photonic Chip: Topologically Controlled Terahertz Confinement
Recently, the research team led by Prof. Xu Jingjun, Prof. Chen Zhigang and Prof. Zhang Xinzheng of Nankai University achieved significant progress on terahertz topological photonics in collaboration with the team led by Prof. Roberto Morandotti of National Research Council of Canada. Based on the SSH-type microstructure, they demonstrated for the first time nonlinear generation and topologically tuned confinement of THz waves in a wedge-shaped lattice formed by an engineered lithium niobate chi
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06.28 2022Nankai Team Discovered a Potential Novel Therapeutical Target for Alzheimer's Disease
Recently, two research teams led by Prof. Zhang Tao and Prof. Wu Shi’an from the College of Life Sciences, Nankai University, collaborated to publish a paper titled MST1 Mediates Neuronal Loss and Cognitive Deficits: A Novel Therapeutic Target for Alzheimers Disease on the online journal of Progress in Neurobiology, whose findings for the first time suggest that MST1-mediated synapse loss is an essential mechanism of cognitive deficits and neuronal loss for Alzheimers disease (AD) and could be a
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06.23 2022NKU Team Made New Progress in Ultra-Low Temperature Treatment of Ozone Pollutants
The research group led by Prof. Wang Weichao of the College of Electronic Information and Optical Engineering, Nankai University, for the first time realized ultra-low temperature (-40℃ - room temperature) ozonolysis with zero energy consumption on the ternary oxide catalyst mullite YMn2O5. The application of this achievement will provide technical support for the decomposition of new atmospheric pollutant ozone in ultra-low temperature environment, and play a role in such fields as commercial a
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06.13 2022NKU Professor Achieved a Breakthrough in Plant Photosynthesis
Professor Li Lei from the College of Life Sciences, Nankai University (NKU) has worked with six international research teams including Professor Harvey Millar from the University of Western Australia and Professor Barry Pogson from the Australian National University to systematically analyze the protein turnover of the model plant Arabidopsis in response to the high light stress by using the protein mass spectrometry analysis platform and discovered the new regulation mechanism of the protein ho
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06.02 2022New Mechanism for Effective Inhibition of Urinary Tract Infection Caused by Pathogenic "Escherichia Coli" Found by A Research Team of Nankai University
Schematic diagram of the mechanism for Uropathogenic Escherichia coli(UPEC) escape from fusiform vesiclesA recent study from a Nankai research team reveals the molecular mechanism of a key vesicle escape step in the pathogenesis of UPEC, and the team finds that silence of host phosphate transporter PIT1 using Accell siRNA can effectively inhibit UPEC infection. This discovery provides new ideas for treating urinary tract infection (UTI). The paper describing aforesaid work is published in intern
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05.16 2022Nankai's team constructed therapeutic agents at lesions in situ with "enzyme amplified peptide assembly"
Recently, Yu Zhilin’s research group from Nankai University published a paper in Journal of the American Chemical Society and proposed a new concept of “enzyme amplified peptide assembly”, which realized the intracellular in situ assembly process at normal enzyme levels through the amplification relationship between polypeptide assembly and enzyme expression, thus providing a new strategy for the early diagnosis and intervention of diseases.Based on previous studies of polypeptide controllable a
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05.11 2022Nankai Scholars Published a Paper in "Nature Reviews Chemistry" on the Post-synthetic Modification of Metal-Organic Cages (MOCs)
The design, synthesis and functional development of Metal-Organic Cages are the frontier fields of the current chemical research. Recently, Zhang Zhenjie, a researcher from the College of Chemistry of Nankai University and Chen Yao, a researcher from the State Key Laboratory of Medicinal Chemical Biology of Nankai University published a paper in the international top journal Nature Reviews Chemistry (IF 34.035) upon invitation under the title: Post-synthetic Modification of Metal-Organic Cages (
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05.09 2022Nankai Team Made Progress in the Research of Mechanical Signal Transduction Mechanism of Intestinal Pathogens
Recently, a Nankai team led by Professor Wang Lei and Professor Feng Lu has made progress in the research of regulation mechanism of pathogenicity of intestinal pathogens. The research results were titled Elucidation of a Complete Mechanical Signaling and Virulence Activation Pathway in Enterohemorrhagic Escherichia Coli and published online Cell Reports.How mechanical signals are converted into biological signals to regulate the life processes is an important biological question, but the resear
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04.27 2022Scientific Research Team from Nankai University Has Made Progress in Artificial Blood Vessel Research
Recently, Professor Kong Deling’s team from College of Life Sciences and the State Key Laboratory of Medicinal Chemical Biology of Nankai University published a research paper entitled Mechanically reinforced biotubes for arterial replacement and arteriovenous grafting inspired by architectural engineering in Science Advances online. Inspired by tunnel construction engineering, this research has constructed in vivo engineered artificial blood vessels reinforced by a polymer fiber skeleton, which
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04.11 2022Genome-scale Screening Identifies Key Genes for Pluripotency Exit of Rat Embryonic Stem Cells (ESCs)
Schematic diagram of the process in which Thop1 affects the pluripotency exit of rat ESCs by affecting the phosphorylation of ERK1/2Recently, the research group led by Researcher Shuai Ling from the State Key Laboratory of Medicinal Chemical Biology of Nankai University has screened the rat haploid ESCs (haESCs) carrying a Rex1-GFP reporter and found that knocking out Thop1 can inhibit the phosphorylation of ERK1/2 and thus retard the pluripotency exit (random differentiation) of rat ESCs. This
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