Recently, the team led by Professor Zhu Yushan from Nankai University College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, and Interdisciplinary Science Center for Cell Response, published the research findings entitled Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression on the journal eLifeonline. The study found that hypoxic stress can affect the molecular mechanism of tumor progression by regulating the ubiquitination modification and
Recently, Yanshan University, Nankai University and some other institutions have collaborated to resolve the long-standing problems about the pathways of the graphite-to-diamond phase transition with high-pressure synthesis method. A new type of graphite-diamond composite material, which combines the electrical conductivity of graphite, the superhardness of diamond, and high toughness that neither graphite nor diamond possesses, has also been created and added to the family of carbon materials.
The Long March-5B Y3 carrier rocket, carrying Wentian lab module, blasted off from the Wenchang Spacecraft Launch Site on July 24, 2022 (Beijing Time). The Wentian lab module then successfully entered the preset orbit and docked with the Tianhe core module about 13 hours later; and the Shenzhou-14 astronauts successfully entered the Wentian lab module.This is the 24th flight mission since the China’s manned space program was initiated. The Wentian lab module marks the second section of the Chine
On July 13, Chinas first vertical take-off and landing (VTOL) jet-powered aircraft had a successful test flight at Tianjin Douzhuang Airport. The aircraft was independently designed and developed by the team of Professor Duan Feng from the College of Artificial Intelligence of Nankai University.This VTOL jet-powered aircraft runs on diesel, with its fuselage free from rotor and external wings. Four to eight small turbojet engines are used as its power source to provide a lift force of 100 kg. Th
Recently, the team headed by Prof. Zhao Mingfeng of the First Central Hospital Affiliated to Nankai University and the team headed by Prof. Zhang Hongkai of the School of Life Sciences of Nankai University cracked the problem of R/R AML CAR-T treatment through cooperation. The relevant findings were published online in the international prestigious Journal of Hematology Oncology (IF:23.168) on July 7.In this clinical study, the teams applied CAR-T cell therapy for the new target CLL-1 to adult
Prof. Li Lei from the College of Life Sciences, Nankai University formed an international joint research team with Prof. Harvey Millar of the University of Western Australia and Prof. Marisa Otegui of the University of Wisconsin. Using stable isotope metabolic labeling and a protein turnover analysis platform created by mass spectrometry technology, in conjunction with cell biology, metabolomics analysis and biochemical experimental evidence, the team systematically compared the differences in t
Recently, the research group headed by Prof. Zhao Qiang from the State Key Laboratory of Medicinal Chemical Biology of Nankai University made new progress in the preparation of new bio-hybrid artificial blood vessels and regulation of their tissue regeneration. The team put forward a new strategy for artificial blood vessels to improve tissue regeneration and restructuring through local release of nitric oxide (NO), and designed and prepared bio-hybrid artificial blood vessels with NO slow-relea
Interventional brain-computer interface was realized on the sheep brain for the first time in ChinaProf. Duan Feng of Nankai University at the experiment siteOn June 25, an animal experiment on Chinas first independently developed interventional Brain-Computer Interface (BCI) was completed in Beijing. The interventional BCI for this experiment was developed by the research team led by Prof. Duan Feng of the College of Artificial Intelligence, Nankai University, in partnership with Shanghai Heart
Bacterial meningitis is one of the top ten causes of infection-related deaths worldwide which has high rates of morbidity and mortality in newborns and the elderly. Neonatal meningitis-causing Escherichia coli(NMEC) is the leading cause of meningitis in newborns worldwide. The brain was long regarded as a highly immuneprivileged site which would benefits for bacterial survival once they invade in the brain. However, recent studies showed that some cells in brain, including microglia and astrocy
Recently, the research team led by Prof. Xu Jingjun, Prof. Chen Zhigang and Prof. Zhang Xinzheng of Nankai University achieved significant progress on terahertz topological photonics in collaboration with the team led by Prof. Roberto Morandotti of National Research Council of Canada. Based on the SSH-type microstructure, they demonstrated for the first time nonlinear generation and topologically tuned confinement of THz waves in a wedge-shaped lattice formed by an engineered lithium niobate chi
Recently, two research teams led by Prof. Zhang Tao and Prof. Wu Shi’an from the College of Life Sciences, Nankai University, collaborated to publish a paper titled MST1 Mediates Neuronal Loss and Cognitive Deficits: A Novel Therapeutic Target for Alzheimers Disease on the online journal of Progress in Neurobiology, whose findings for the first time suggest that MST1-mediated synapse loss is an essential mechanism of cognitive deficits and neuronal loss for Alzheimers disease (AD) and could be a
The research group led by Prof. Wang Weichao of the College of Electronic Information and Optical Engineering, Nankai University, for the first time realized ultra-low temperature (-40℃ - room temperature) ozonolysis with zero energy consumption on the ternary oxide catalyst mullite YMn2O5. The application of this achievement will provide technical support for the decomposition of new atmospheric pollutant ozone in ultra-low temperature environment, and play a role in such fields as commercial a
Professor Li Lei from the College of Life Sciences, Nankai University (NKU) has worked with six international research teams including Professor Harvey Millar from the University of Western Australia and Professor Barry Pogson from the Australian National University to systematically analyze the protein turnover of the model plant Arabidopsis in response to the high light stress by using the protein mass spectrometry analysis platform and discovered the new regulation mechanism of the protein ho
Schematic diagram of the mechanism for Uropathogenic Escherichia coli(UPEC) escape from fusiform vesiclesA recent study from a Nankai research team reveals the molecular mechanism of a key vesicle escape step in the pathogenesis of UPEC, and the team finds that silence of host phosphate transporter PIT1 using Accell siRNA can effectively inhibit UPEC infection. This discovery provides new ideas for treating urinary tract infection (UTI). The paper describing aforesaid work is published in intern
Recently, Yu Zhilin’s research group from Nankai University published a paper in Journal of the American Chemical Society and proposed a new concept of “enzyme amplified peptide assembly”, which realized the intracellular in situ assembly process at normal enzyme levels through the amplification relationship between polypeptide assembly and enzyme expression, thus providing a new strategy for the early diagnosis and intervention of diseases.Based on previous studies of polypeptide controllable a